Protein remover tablets (RGP)

For wearers of RGP (Rigid Gas Permeable) contact lenses, protein remover tablets used to work better than enzymatic liquids. The tablets seem to be unavailable in Toronto (or online in Canada). The older hydrogen peroxide-based solutions not only have antimicrobial benefits, but also remove protein buildup.

Hydrogen peroxide lens care solutions kill microorganisms by producing free radicals that destroy cell membranes and essential cell components.11,12 This contrasts with MPS systems that use polyhexamethylene biguanide (PHMB), which acts on bacterial chromosomes12,13 or with alexidine and polyquaternium-1 (PQ), which interact with cell membranes and disrupt the membrane structure.12–14 Irrespective of mechanism, the disinfecting solutions must be capable of killing a broad range of microorganisms as prescribed by ISO and FDA standards.5,15 The disinfection tests are typically carried out against planktonic (floating in liquid) microorganisms, whereas it is known that, once adherent to a surface, bacteria will cover themselves with a protective biofilm that renders them more difficult to kill. Testing against bacterial and fungal biofilms showed that hydrogen peroxide disinfection performs better than a range of MPS

Gabriel, M. M., McAnally, C., Chen, H., Srinivasan, S., Manoj, V., & Garofalo, R. (2021). Hydrogen Peroxide Disinfecting Solution for Gas Permeable Contact Lenses: A Review of the Antimicrobial Efficacy, Compatibility, and Safety Performance of a One-Step Lens Care System. Clinical optometry13, 7–14.

There are multiple brands of hydrogen peroxide-based solutions available.

Hydrogen Peroxide Based Cleaners
These solutions use hydrogen peroxide as one or two-step cleansing options to both disinfect lenses, clean the surface of debris and build-up, and store overnight.  They both require 6 hours of cleaning time to fully disinfect the lenses.

Manicam, C., Perumal, N., Wasielica-Poslednik, J. et al. Proteomics Unravels the Regulatory Mechanisms in Human Tears Following Acute Renouncement of Contact Lens Use: A Comparison between Hard and Soft Lenses. Sci Rep 8, 11526 (2018).

#contact-lens, #protein-remover, #rgp